(E)-5-Chloro-3-(2,6-dichlorobenzylidene)indolin-2-one
نویسندگان
چکیده
There are two independent mol-ecules of the title compound, C(15)H(8)Cl(3)NO, in the asymmetric unit. Both form inversion dimers via pairs of hydrazide-carbonyl N-H⋯O hydrogen bonds.
منابع مشابه
(E)-5-Bromo-3-(2,6-dichlorobenzylidene)indolin-2-one
The title compound, C(15)H(8)BrCl(2)NO, crystallizes with two independent mol-ecules in the asymmetric unit. The dihedral angles between the two aromatic rings are 62.74 (9) and 63.50 (6)° in the two independent molecules. In the crystal, the mol-ecules are connected by N-H⋯O hydrogen bonds, forming two centrosymmetric dimers.
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There are two independent mol-ecules in the asymmetric unit of the title compound, C(15)H(9)Cl(2)NO. The dihedral angles between the oxindolyl and dichloro-phenyl rings are essentially identical for the two independent mol-ecules [63.4 (1) and 63.2 (1)°]. Dimers linked by amide-carbonyl N-H⋯O hydrogen bonds are formed from each symmetry-independent mol-ecule and the respective symmetry equivale...
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The title compound, C13H13Cl2NO, has a 3-(propan-2-yl-idene)indolin-2-one core with a Cl atom and a chloro-ethyl substituent attached to the aromatic ring. Two atoms of the aromatic ring and the chloro-ethyl substituent atoms are disordered over two sets of sites with a refined occupancy ratio of 0.826 (3):0.174 (3). In the crystal, mol-ecules are linked by pairs of N-H⋯O hydrogen bonds, formin...
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The reference standard CX-6258 {(E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one, 4a} and its desmethylated precursor N-desmethyl-CX-6258 {(E)-3-((5-(3-(1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)-5-chloroindolin-2-one, 5} for radiolabeling were synthesized from 5-bromo-2-furaldehyde and 3-carboxybenzeneboronic acid in 3 and 4 steps wi...
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